Chronic Inflammatory Demyelinating Polyneuropathy

Overview

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a neurological disorder characterised by progressive inflammation of peripheral nerves, leading to weakness, numbness, and impaired coordination. It occurs when the body’s immune system mistakenly attacks the protective layer (myelin sheath) around nerves, affecting their ability to transmit signals properly.

At Royal Buckinghamshire Hospital, we specialise in diagnosing, treating, and rehabilitating patients with CIDP, providing tailored care aimed at improving nerve function, mobility, and overall quality of life.

Causes of CIDP

CIDP is considered an autoimmune disorder, though the exact cause remains unknown. Potential triggers or risk factors include:

• Autoimmune conditions
• Recent infections
• Genetic susceptibility (in rare cases)
• Sometimes, no specific cause is identified

Symptoms of CIDP

Symptoms typically develop gradually over several weeks or months and can include:

• Progressive muscle weakness, often starting in the legs and arms
• Tingling, numbness, or sensory changes in hands and feet
• Balance difficulties and impaired coordination
• Fatigue and reduced stamina
• Muscle cramps or spasms
• Difficulty walking or climbing stairs

CIDP symptoms can fluctuate, with periods of improvement and worsening over time.

Diagnosis at Royal Buckinghamshire Hospital

Our specialist neurologists provide comprehensive diagnostic evaluations, including:

• Thorough neurological examination
• Nerve conduction studies (electromyography – EMG)
• Lumbar puncture to assess cerebrospinal fluid for signs of inflammation
• Blood tests to rule out other autoimmune conditions or infections
• MRI imaging in selected cases to exclude other neurological disorders

Early and accurate diagnosis enables timely treatment and rehabilitation.

Treatment & Rehabilitation

WhCIDP treatment at Royal Buckinghamshire Hospital is focused on managing symptoms, reducing inflammation, and improving nerve function:

Medical Treatments:

• Intravenous immunoglobulin (IVIG) therapy to modulate immune response
• Corticosteroids to reduce inflammation
• Plasma exchange (plasmapheresis) in severe or unresponsive cases
• Immunosuppressant medications, if necessary

Rehabilitation Services:

• Psychological support to address emotional wellbeing and coping strategies
• Specialist physiotherapy to strengthen muscles, improve balance, and maintain mobility
• Occupational therapy to enhance daily living skills and independence
• Pain management strategies tailored to individual needs
• Assistive technology and mobility aids to support independence and safety

Why Choose Royal Buckinghamshire Hospital?

• Specialist neurological and rehabilitation expertise
• Individualised, multidisciplinary care plans
• State-of-the-art diagnostic and therapeutic services
• Inpatient and outpatient rehabilitation programmes
• Compassionate, private patient-focused environment

Our Resident Neurologist

Dr Weatherall is very welcoming and highly experienced. He offers his patients sound diagnosis and treatment, along with individual care focused on their future health.

Dr Mark Weatherall

Consultant Neurologist

Field